Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Clec2d Joins the Cell Death Sensor Ranks.

Del Fresno, Carlos; Sancho, David.

Immunity ; 52(1): 6-8, 2020 01 14.

Artigo em Inglês | MEDLINE | ID: mdl-31951550

2.

A Neutrophil Timer Coordinates Immune Defense and Vascular Protection.

Adrover, José M; Del Fresno, Carlos; Crainiciuc, Georgiana; Cuartero, Maria Isabel; Casanova-Acebes, María; Weiss, Linnea A; Huerga-Encabo, Hector; Silvestre-Roig, Carlos; Rossaint, Jan; Cossío, Itziar; Lechuga-Vieco, Ana V; García-Prieto, Jaime; Gómez-Parrizas, Mónica; Quintana, Juan A; Ballesteros, Ivan; Martin-Salamanca, Sandra; Aroca-Crevillen, Alejandra; Chong, Shu Zhen; Evrard, Maximilien; Balabanian, Karl; López, Jorge; Bidzhekov, Kiril; Bachelerie, Françoise; Abad-Santos, Francisco; Muñoz-Calleja, Cecilia; Zarbock, Alexander; Soehnlein, Oliver; Weber, Christian; Ng, Lai Guan; Lopez-Rodriguez, Cristina; Sancho, David; Moro, María A; Ibáñez, Borja; Hidalgo, Andrés.

Immunity ; 50(2): 390-402.e10, 2019 02 19.

Artigo em Inglês | MEDLINE | ID: mdl-30709741

3.

Distinct Compartmentalization of the Chemokines CXCL1 and CXCL2 and the Atypical Receptor ACKR1 Determine Discrete Stages of Neutrophil Diapedesis.

Girbl, Tamara; Lenn, Tchern; Perez, Lorena; Rolas, Loïc; Barkaway, Anna; Thiriot, Aude; Del Fresno, Carlos; Lynam, Eleanor; Hub, Elin; Thelen, Marcus; Graham, Gerard; Alon, Ronen; Sancho, David; von Andrian, Ulrich H; Voisin, Mathieu-Benoit; Rot, Antal; Nourshargh, Sussan.

Immunity ; 49(6): 1062-1076.e6, 2018 12 18.

Artigo em Inglês | MEDLINE | ID: mdl-30446388

4.

Neutrophils acROSs the Enemy Lines.

Del Fresno, Carlos; Hidalgo, Andrés.

Immunity ; 46(3): 335-337, 2017 03 21.

Artigo em Inglês | MEDLINE | ID: mdl-28329696

5.

Optimal Generation of Tissue-Resident but Not Circulating Memory T Cells during Viral Infection Requires Crosspriming by DNGR-1⁺ Dendritic Cells.

Iborra, Salvador; Martínez-López, María; Khouili, Sofía C; Enamorado, Michel; Cueto, Francisco J; Conde-Garrosa, Ruth; Del Fresno, Carlos; Sancho, David.

Immunity ; 45(4): 847-860, 2016 10 18.

Artigo em Inglês | MEDLINE | ID: mdl-27692611

6.

Leishmania Uses Mincle to Target an Inhibitory ITAM Signaling Pathway in Dendritic Cells that Dampens Adaptive Immunity to Infection.

Iborra, Salvador; Martínez-López, María; Cueto, Francisco J; Conde-Garrosa, Ruth; Del Fresno, Carlos; Izquierdo, Helena M; Abram, Clare L; Mori, Daiki; Campos-Martín, Yolanda; Reguera, Rosa María; Kemp, Benjamin; Yamasaki, Sho; Robinson, Matthew J; Soto, Manuel; Lowell, Clifford A; Sancho, David.

Immunity ; 45(4): 788-801, 2016 10 18.

Artigo em Inglês | MEDLINE | ID: mdl-27742545

7.

A Neutrophil Timer Coordinates Immune Defense and Vascular Protection.

Adrover, José M; Del Fresno, Carlos; Crainiciuc, Georgiana; Cuartero, Maria Isabel; Casanova-Acebes, María; Weiss, Linnea A; Huerga-Encabo, Hector; Silvestre-Roig, Carlos; Rossaint, Jan; Cossío, Itziar; Lechuga-Vieco, Ana V; García-Prieto, Jaime; Gómez-Parrizas, Mónica; Quintana, Juan A; Ballesteros, Ivan; Martin-Salamanca, Sandra; Aroca-Crevillen, Alejandra; Chong, Shu Zhen; Evrard, Maximilien; Balabanian, Karl; López, Jorge; Bidzhekov, Kiril; Bachelerie, Françoise; Abad-Santos, Francisco; Muñoz-Calleja, Cecilia; Zarbock, Alexander; Soehnlein, Oliver; Weber, Christian; Ng, Lai Guan; Lopez-Rodriguez, Cristina; Sancho, David; Moro, María A; Ibáñez, Borja; Hidalgo, Andrés.

Immunity ; 51(5): 966-967, 2019 Nov 19.

Artigo em Inglês | MEDLINE | ID: mdl-31747583

8.

SARS-CoV-2 Proteins Induce Endotoxin Tolerance Hallmarks: A Demonstration in Patients with COVID-19.

Avendaño-Ortiz, José; Lozano-Rodríguez, Roberto; Martín-Quirós, Alejandro; Maroun-Eid, Charbel; Terrón-Arcos, Verónica; Montalbán-Hernández, Karla; Valentín, Jaime; Muñoz Del Val, Elena; García-Garrido, Miguel A; Del Balzo-Castillo, Álvaro; Casalvilla-Dueñas, José Carlos; Peinado, María; Gómez, Laura; Herrero-Benito, Carmen; Rubio, Carolina; Cubillos-Zapata, Carolina; Pascual-Iglesias, Alejandro; Del Fresno, Carlos; Aguirre, Luis A; López-Collazo, Eduardo.

J Immunol ; 207(1): 162-174, 2021 07 01.

Artigo em Inglês | MEDLINE | ID: mdl-34183364

9.

COVID-19 vaccine candidates based on modified vaccinia virus Ankara expressing the SARS-CoV-2 spike induce robust T- and B-cell immune responses and full efficacy in mice.

García-Arriaza, Juan; Garaigorta, Urtzi; Pérez, Patricia; Lázaro-Frías, Adrián; Zamora, Carmen; Gastaminza, Pablo; Del Fresno, Carlos; Casasnovas, José M; Sorzano, Carlos Óscar S; Sancho, David; Esteban, Mariano.

J Virol ; 95(7)2021 03 10.

Artigo em Inglês | MEDLINE | ID: mdl-33414159

10.

cDC1s: New Orchestrators of Tissue Innate Immunity.

Del Fresno, Carlos; Sancho, David.

Trends Immunol ; 40(7): 559-561, 2019 07.

Artigo em Inglês | MEDLINE | ID: mdl-31133464

11.

Interferon-ß production via Dectin-1-Syk-IRF5 signaling in dendritic cells is crucial for immunity to C. albicans.

del Fresno, Carlos; Soulat, Didier; Roth, Susanne; Blazek, Katrina; Udalova, Irina; Sancho, David; Ruland, Jürgen; Ardavín, Carlos.

Immunity ; 38(6): 1176-86, 2013 Jun 27.

Artigo em Inglês | MEDLINE | ID: mdl-23770228

12.

Fused Cells between Human-Adipose-Derived Mesenchymal Stem Cells and Monocytes Keep Stemness Properties and Acquire High Mobility.

Montalbán-Hernández, Karla; Casado-Sánchez, Cesar; Avendaño-Ortiz, José; Casalvilla-Dueñas, José Carlos; Bonel-Pérez, Gloria C; Prado-Montero, Julia; Valentín-Quiroga, Jaime; Lozano-Rodríguez, Roberto; Terrón-Arcos, Verónica; de la Bastida, Fátima Ruiz; Córdoba, Laura; Laso-García, Fernando; Diekhorst, Luke; Del Fresno, Carlos; López-Collazo, Eduardo.

Int J Mol Sci ; 23(17)2022 Aug 26.

Artigo em Inglês | MEDLINE | ID: mdl-36077075

13.

Sensing Tissue Damage by Myeloid C-Type Lectin Receptors.

Del Fresno, Carlos; Cueto, Francisco J; Sancho, David.

Curr Top Microbiol Immunol ; 429: 117-145, 2020.

Artigo em Inglês | MEDLINE | ID: mdl-31974758

14.

Dectin-1/2-induced autocrine PGE2 signaling licenses dendritic cells to prime Th2 responses.

Kaisar, Maria M M; Ritter, Manuel; Del Fresno, Carlos; Jónasdóttir, Hulda S; van der Ham, Alwin J; Pelgrom, Leonard R; Schramm, Gabriele; Layland, Laura E; Sancho, David; Prazeres da Costa, Clarissa; Giera, Martin; Yazdanbakhsh, Maria; Everts, Bart.

PLoS Biol ; 16(4): e2005504, 2018 04.

Artigo em Inglês | MEDLINE | ID: mdl-29668708

15.

SHIP-1 Couples to the Dectin-1 hemITAM and Selectively Modulates Reactive Oxygen Species Production in Dendritic Cells in Response to Candida albicans.

Blanco-Menéndez, Noelia; Del Fresno, Carlos; Fernandes, Sandra; Calvo, Enrique; Conde-Garrosa, Ruth; Kerr, William G; Sancho, David.

J Immunol ; 195(9): 4466-4478, 2015 Nov 01.

Artigo em Inglês | MEDLINE | ID: mdl-26416276

16.

NFκB2/p100 is a key factor for endotoxin tolerance in human monocytes: a demonstration using primary human monocytes from patients with sepsis.

Cubillos-Zapata, Carolina; Hernández-Jiménez, Enrique; Toledano, Víctor; Esteban-Burgos, Laura; Fernández-Ruíz, Irene; Gómez-Piña, Vanesa; Del Fresno, Carlos; Siliceo, María; Prieto-Chinchiña, Patricia; Pérez de Diego, Rebeca; Boscá, Lisardo; Fresno, Manuel; Arnalich, Francisco; López-Collazo, Eduardo.

J Immunol ; 193(8): 4195-202, 2014 Oct 15.

Artigo em Inglês | MEDLINE | ID: mdl-25225662

17.

p38Î³ and p38Î´ kinases regulate the Toll-like receptor 4 (TLR4)-induced cytokine production by controlling ERK1/2 protein kinase pathway activation.

Risco, Ana; del Fresno, Carlos; Mambol, Agnes; Alsina-Beauchamp, Dayanira; MacKenzie, Kirsty F; Yang, Huei-Ting; Barber, Domingo F; Morcelle, Carmen; Arthur, J Simon C; Ley, Steven C; Ardavin, Carlos; Cuenda, Ana.

Proc Natl Acad Sci U S A ; 109(28): 11200-5, 2012 Jul 10.

Artigo em Inglês | MEDLINE | ID: mdl-22733747

18.

IL-4 blocks TH1-polarizing/inflammatory cytokine gene expression during monocyte-derived dendritic cell differentiation through histone hypoacetylation.

López-Bravo, María; Minguito de la Escalera, María; Domínguez, Pilar M; González-Cintado, Leticia; del Fresno, Carlos; Martín, Pilar; Martínez del Hoyo, Gloria; Ardavín, Carlos.

J Allergy Clin Immunol ; 132(6): 1409-19, 2013 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-24139608

19.

Endotoxin tolerance and trained immunity: breaking down immunological memory barriers.

López-Collazo, Eduardo; Del Fresno, Carlos.

Front Immunol ; 15: 1393283, 2024.

Artigo em Inglês | MEDLINE | ID: mdl-38742111

20.

Heat-killed Mycobacterium tuberculosis induces trained immunity in vitro and in vivo administered systemically or intranasally.

Minute, Luna; Bergón-Gutiérrez, Marta; Mata-Martínez, Pablo; Fernández-Pascual, Jaime; Terrón, Verónica; Bravo-Robles, Laura; Biçakcioglu, Gülce; Zapata-Fernández, Gabriela; Aguiló, Nacho; López-Collazo, Eduardo; Del Fresno, Carlos.

iScience ; 27(2): 108869, 2024 Feb 16.

Artigo em Inglês | MEDLINE | ID: mdl-38318361

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Clec2d Joins the Cell Death Sensor Ranks.

A Neutrophil Timer Coordinates Immune Defense and Vascular Protection.

Distinct Compartmentalization of the Chemokines CXCL1 and CXCL2 and the Atypical Receptor ACKR1 Determine Discrete Stages of Neutrophil Diapedesis.

Neutrophils acROSs the Enemy Lines.

Optimal Generation of Tissue-Resident but Not Circulating Memory T Cells during Viral Infection Requires Crosspriming by DNGR-1⁺ Dendritic Cells.

Leishmania Uses Mincle to Target an Inhibitory ITAM Signaling Pathway in Dendritic Cells that Dampens Adaptive Immunity to Infection.

A Neutrophil Timer Coordinates Immune Defense and Vascular Protection.

SARS-CoV-2 Proteins Induce Endotoxin Tolerance Hallmarks: A Demonstration in Patients with COVID-19.

COVID-19 vaccine candidates based on modified vaccinia virus Ankara expressing the SARS-CoV-2 spike induce robust T- and B-cell immune responses and full efficacy in mice.

cDC1s: New Orchestrators of Tissue Innate Immunity.

Interferon-ß production via Dectin-1-Syk-IRF5 signaling in dendritic cells is crucial for immunity to C. albicans.

Fused Cells between Human-Adipose-Derived Mesenchymal Stem Cells and Monocytes Keep Stemness Properties and Acquire High Mobility.

Sensing Tissue Damage by Myeloid C-Type Lectin Receptors.

Dectin-1/2-induced autocrine PGE2 signaling licenses dendritic cells to prime Th2 responses.

SHIP-1 Couples to the Dectin-1 hemITAM and Selectively Modulates Reactive Oxygen Species Production in Dendritic Cells in Response to Candida albicans.

NFκB2/p100 is a key factor for endotoxin tolerance in human monocytes: a demonstration using primary human monocytes from patients with sepsis.

p38Î³ and p38Î´ kinases regulate the Toll-like receptor 4 (TLR4)-induced cytokine production by controlling ERK1/2 protein kinase pathway activation.

IL-4 blocks TH1-polarizing/inflammatory cytokine gene expression during monocyte-derived dendritic cell differentiation through histone hypoacetylation.

Endotoxin tolerance and trained immunity: breaking down immunological memory barriers.

Heat-killed Mycobacterium tuberculosis induces trained immunity in vitro and in vivo administered systemically or intranasally.